Serratia marcescens serratia is a genus in the enterobacteriaceae family. Most microbiologists and clinicians pronounce the name sir eh sha, but a minority including me pronounce it sir ah tee uh. The biochemical, serological, and epidemiological characteristics of 95 strains of serratia marcescens isolated at the boston city hospital were examined. Entradas sobre serratia marcescens escritas por cienciamx. The swarmer cells can range in length from 530 m and they are highly flagellated and nonseptated. Serratia marcescens is motile and travels by several different means. Once considered a harmless saprophyte, serratia marcescens is now recognized as an important opportunistic pathogen combining a propensity for healthcareassociated infection and antimicrobial resistance. In the meantime, widespread use of quinolones has resulted in an increasing incidence of quinoloneresistant s. Endonucleolytic cleavage to 5phosphomononucleotide and 5phosphooligonucleotide endproducts.
The primary structure and physical chemical properties were determined of a nuclease expressed and secreted by escherichia coli. Serratia marcescens efflux pumps there are six efflux pumps found in s. Dec 17, 2011 serratia marcescens is a human pathogenic species of serratia. Purification and characterization of a serratia marcescens. This enzyme catalyses the following chemical reaction. As a group they can swarm together on agar of lower concentrations 0.
Serratia marcescens definition of serratia marcescens by. In immunocompromised patients, they can cause wound infections, infections of the kidney and urinary tract, respiratory tract infections and sepsis. The disease is commonly known as either serratia plymuthica, serratia liquefaciens, serratia rubidaea, serratia odorifera, or serratia fonticola. The serratia species are occasionally recognized as a cause of hospital acquired infections such as urinary tract infections, respiratory tract.
Serratia marcescens synonyms, serratia marcescens pronunciation, serratia marcescens translation, english dictionary definition of serratia marcescens. Serratia marcescens is an important cause of nosocomial infections in both human and veterinary medicine. It is an airborne bacterium, meaning it travels in the air as tiny particles. There have been many reports concerning the identification, antibiotic susceptibility, pathogenicity, epidemiological investigations and typing of this organism. View serratia marcescens research papers on academia. Total viable bacterial counts and total potential serratia marcescens counts. A gramnegative bacillus of the enterobacteriaceae family, serratia marcescens is an organism known to cause bacteremia, pneumonia, urinary tract infection, endocarditis, meningitis, and septic arthritis. Serratia marcescens is a rare opportunistic bacterium that is categorized in the enterobateriaceae family commonly found in the environment. It is commonly found in the respiratory and urinary tracts of hospitalized adults and in the gastrointestinal system of. The api 20e system has been used widely, but is not individually.
Serratia marcescens, a motile, gram negative bacillus, which has been classified as a member of the family, enterobacteriaceae, is widespread in the environment, but it is a rare cause of human disease. Seven patients survived the septicemia, nine did not. In the absence of a food source, it will even feed upon itself if all. Identification of a serratia marcescens clinical isolate with. Serratia marcescens mediumsized colonies that appear buff in colour on blood agar. Although serratia is now recognized as a human pathogen, it has a literally colorful history in medical microbiology. Serratia marcescens the type species of the genus serratia. Serratia marcescens and serratia liquefaciens are mainly cause of hospitalacquired infections. The bacteria produce a red pigment which is easily seen when grown on bloodfree media such as nutrient agar or kings agar b.
Several strains were shown to be endemic, and the majority of isolates were cultured from urine or respiratory secretions. Tehran, iran 2d ep a rtmn of fss c i,u lyt hu v b c b 4. Serratia marcescens different drug resistant efflux pumps. Studies of the enzymology and the structures of the enzymes provide insight in how a natural set of. As part of a bioweapon experiment, serratia marcescens pictured on an agar plate above was released in san francisco back in 1950. Serratia marcescens is commonly found in soil, water, plants and animals. International journal of systematic and evolutionary microbiology 53. The bacteria can produce prodigiosin, a pigment color that ranges from lights pink to dark red. Most serratia species are nonpathogenic, but those that are pathogenic typically cause infection in immunocompromised individuals. The color can identify the age of the bacterial colony which thrives in the soil, water, and the digestive.
Review of prodigiosin, pigmentation in serratia marcescens 1a n it akh f r, 1,2 m ah nz er ia s d 1 fat e m ha di k r 1department of microbiological sciences, islamic azad university, 4th floor, north of tehran, darband str. Serratia marcescens e uma bacteria gramnegativa pertencente a familia enterobacteriaceae. The pigment can be present after incubation at room temperature but usually disappears after subculturing. In immunocompromised patients, they can cause wound infections, infections of the kidney and urinary tract, respiratory tract infections and sepsis, endocarditis, meningitis, and prosthetic infections.
Serratia marcescens historical perspective and clinical. Serratia marcescens a rare opportunistic nosocomial. Summary over the last 30 years, serratia marcescens has become an important cause of nosocomial infection. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Carbapenem resistance among gramnegative non fermentative bacteria is widely known, whereas carbapenem resistance among enterobacteriaceae is rare. An opportunistic human pathogen, serratia marcescens is involved in nosocomial infections, particularly catheterassociated bacteremia, urinary tract infections and wound infections, and is responsible for 1. Sykes, in canine and feline infectious diseases, 2014. In this study we describe a case of sepsis caused by serratia marcescens carrying blakpc gene. S7992 serratia marcescens subspecies marcescens bizio 1823 date of change. Review of prodigiosin, pigmentation in serratia marcescens. Necrotizing cellulitis with multiple abscesses on the leg. Por ello es comun encontrarla en ambientes humedos como banos, desagues, fregaderos, lavamanos, etc. Serratia marcescens septicemia jama internal medicine. The mode of transmission of this microorganism is by either direct contact,or by.
Several strains were shown to be endemic, and the majority of isolates were cultured from urine or. Serratia marcescens is a human pathogenic species of serratia. Serratia marcescens an emerging pathogen serratia marcescens is a species of gramnegative, rodshaped bacterium in the family enterobacteriaceae. This microorganism has a romantic history dating to antiquity, when, because of prod. Pdf on jan 1, 2003, ruizsanchez a and others published serratia marcescens. Serratia marcescens is a member of the genus serratia, which is a part of the family enterobacteriaceae.
Sdeab serratias drug effluxit is an rndtype resistancenodulationcell division efflux pump with genes that code for both an mf and rndtype efflux pumps. Serratia marcescens is a motile,short rodshaped, gramnegative, facultative anaerobe bacterium, classified as an opportunistic pathogen. Serratia marcescens is a bacterium recognized with increasing frequency as a cause of serious infection in man. Serratia marcescens is one of the most effective bacteria for degradation of chitin, a 1,4. Currently, four species of serratia have been found in sea water. Bizio named the genus serratia in honor of and italian physicist named serratia, and chose marcescens for the species name after the latin word. Serratia marcescens infectious disease and antimicrobial agents. All survivors had organisms sensitive to at least one antibiotic and had been treated with the appropriate antibiotic. A single serratia marcescens bacterium can swim with the use of its flagellum. In human patients it is often linked to intravenous drug use. Serratia marcescens can be deadly in humans as documented in 1996 when the center for.
Jul 06, 2015 as part of a bioweapon experiment, serratia marcescens pictured on an agar plate above was released in san francisco back in 1950. The organism has a tremendous ability to survive in the environment and may contaminate and remain viable in disinfectant solutions. It was discovered in 1819 by bartolomeo bizio in padua, italy. Identification of a serratia marcescens clinical isolate. S2701 serratia marcescens bizio 1823 date of change. It is commonly found in the respiratory and urinary tracts of hospitalized adults. It is pink in appearance, and it thrives in moist, damp conditions and feeds on the residue of soaps and shampoos. Serratia marcescens, a gramnegative bacillus that belongs to the family enterobacteriaceae, is an opportunistic pathogen that can cause many types of nosocomial infections. Various strains of serratia occupy an eclectic range of habitats. The plasmid p403sd2 carried a dna sequence isolated from serratia marcescens encoding the enzyme.
It is associated with urinary and respiratory infections, endocarditis, osteomyelitis, septicemia, wound infections, eye infections, and meningitis. Serratia marcescens an overview sciencedirect topics. Soil sample microbiological studies were conducted and revealed the presence of bacteria in soil samples obtained from the different sites of the allahabad region of uttar pradesh, india. In brazil, cases of kpc have been reported in klebsiella pneumoniae and escherichia coli, which shows the. Serratia is a genus in the enterobacteriaceae family. Serratia marcescens wikipedia, a enciclopedia livre. Accurate identification is important in defining outbreaks. May 17, 2012 serratia marcescens an emerging pathogen serratia marcescens is a species of gramnegative, rodshaped bacterium in the family enterobacteriaceae.
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